Research

Research

CNSA Research Group Photo

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The CNSA has been at the forefront of patient-centered clinical research related to disorders of aging and cognition. Our investigators are funded by the National Institutes of Health/National Institute on Aging, the State of Florida Ed and Ethel Moore Alzheimer’s Disease Research Program, and other agencies. Our investigative team collaborates with scientists across the globe and have established collaborations with academic partners in Europe, South America, Mexico and beyond to join our efforts in improving outcomes for patients with neurodegenerative conditions and their families.
We offer state-of-the-art clinical trials that are studying Alzheimer’s disease prevention in persons who are at-risk for developing the disease, and have innovated novel cognitive assessment paradigms and technologically-enhanced instruments that are uniquely sensitive to the earliest changes in cognition, and are appropriate for diverse culture/language groups. In addition, our Center develops and implements state-of-the-art cognitive training programs for older adults at-risk for cognitive decline through our Brain Fitness Pavilion.

Areas of research projects funded include, but are not limited to :

  • Aging and Cognition
    • Normal Age Related Changes in Cognition
    • Alzheimer’s Disease and Memory Disorders
    • HIV/AIDS
  • “Functional Skills Training Study”
  • Aging and Functional Performance
  • Telemedicine and eHealth Applications
  • Technology Interventions for Older Adults
  • Family Caregiving
    • UM Working Caregivers

Actively Enrolling Studies

Older AA Adults At-Risk for Alzheimer’s Disease Registry (AAR)

The focus of the AAR study is to work with Researchers throughout the state to study the aging brain and learn more about how to detect and treat brain changes in African Americans that affect memory.

What’s included:

• Memory test
• Blood collection for genetic testing and blood markers
MRI brain scan
• Compensation will be provided. Study Length: 1 visit

Study Requirements:

• Age 60+
• Fasting for blood collection
• Study partner

Contact: Aja Scott 305.355.9089

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Assessment Innovations in Mild Cognitive Impairment (AIM)

The aim of this study is to see whether our new tests can detect changes in memory and thinking abilities better than commonly used tests among Hispanic and non-Hispanic persons with normal cognition or Memory complaints.

What’s included:

• Memory test
• Blood collection for genetic testing
MRI brain scan
• Lumbar puncture (optional)
• Compensation will be provided. Study Length: Annual visit (Continuous)

Study Requirements:

• 60+
• Annual follow up visits
• Study partner

Contact: Ingrid Usaga 305.355.9037

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Novel Computerized Cognitive Stress Test (CST)

The focus of the CST study is to measure the normal aging brain and those with early signs of memory loss. This will be achieved by correlating cognitive markers with biomarkers of preclinical Alzheimer’ disease.

What’s included:

• Memory test
• Blood collection for genetic testing
• Brain PET scan
MRI brain scan
• Lumbar puncture (optional)
• Compensation will be provided. Study Length: Annual visit (Continuous)

Study Requirements:

• 60+
• Annual follow up visits
• Study partner

Contact: Ingrid Usaga 305.355.9037

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Assessment of Middle-aged Offspring of Late Alzheimer’s Probands (OLOAD)

Investigators are studying middle-aged children with at least one parent diagnosed with Alzheimer’s disease to learn more about early markers of risk including cognitive changes, and brain-related functions.

What’s included:

• Memory test
• Blood collection for genetic testing and blood makers
MRI brain scan
• Compensation will be provided. Study Length: 1 visit

Study Requirements:

• 35-59 years old
• Study partner
• Fasting for blood collection

Contact: Sindy Jaramillo 305.355.9062

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Development of Novel Measures of Cognition and Function for Alzheimer’s Disease Prevention Trials: NOMAD

This project examines the usefulness of traditional measures used to measure treatment outcomes as compared to a set of novel measures. This study is for caregivers or healthy adult looking to help further the research on cognitive impairment and Alzheimer’s disease?

What’s included:

• Memory test
MRI brain scan
• Compensation may be provided.

Study Requirements:

• Caregiver or healthy adult
• 60-85 years old

Contact: Behavioral Research Assessment Center (BRAC) at 305.243.5840

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